Characterization of donepezil prepared by cogrinding with salicylic acid and p-aminobenzoic acid
نویسندگان
چکیده
منابع مشابه
INHIBITION OF ESCHERICHIA COLI BY p-AMINOBENZOIC ACID AND ITS REVERSAL BY p-HYDROXYBENZOIC ACID
p-Aminobenzoic acid (PABA) exerts three metabolic effects on E. coli: it acts as a normal vitamin at low concentrations, as a source of another vitamin, p-hydroxybenzoic acid (POB), at moderate concentrations, and as a growth inhibitor at high concentrations (150 to 1600 microg./ml.). The inhibition is competitively reversed by POB in 1/100 the concentration of PABA. The inhibition is also reve...
متن کاملstudy of dna interaction with ethylenediaminetetraacetic acid and sesamol food additives
برهمکنش dnaتیموس گاوی طبیعی (ct-dna) با اتیلن دی آمین تترااستات (edta)در بافرtris-hcl با 8/7 ph ( دراین ph،edta به نمک دی سدیم تبدیل می شود) وسسامول در بافر tris-hcl با4/7 ph مورد بررسی قرار گرفته است. edta و سسامول استفاده فراوانی در تکنولوژی غذایی و صنعت شیمیایی دارند. مدل اتصال dna مربوط بهedta بوسیله اسپکتروفتومتری جذب، دورنگ نمایی حلقوی(cd)، ویسکومتری وژل الکتروفورز بررسی شده است. طیفuv ...
15 صفحه اولSeparation of p-Aminobenzoic Acid Derivatives
According to the literature, p-aminobenzoic acid (PAB) is excreted in the urine mostly as the free acid and its N-acetyl derivative; the remaining part is eliminated conjugated with glucuronic acid and as p-aminohippuric acid (PAH) (Ellinger & Hensel, 1914'; Hensel, 1914; Cohen & McGilvery, 1946; Salassa, Bollman & Dry, 1948). There is no agreement concerning the formation of PAH. Thus, Beyer, ...
متن کاملMechanism of competitive inhibition of p-aminobenzoic acid oxidation by p-aminosalicylic acid.
The proposed mechanism(s) associated with the inhibition of essential metabolic reactions by various compounds has received a great deal of attention in recent years, since antimetabolites have proved useful in several chemotherapeutic areas and in studying various metabolic reactions. The significance of p-aminobenzoic acid in microbial nutrition was first emphasized when Woods (1940) and Wood...
متن کاملIII. COUPLING OF ACETYLATED BOVIXE SERUM ALBUMIN WITH ARSANILIC ACID AND p-AMINOBENZOIC ACID*
In the first report (1) of this series, we described a spectroscopic method for the determination and differentiation of the azo dyes resulting from coupling of arsanilic acid and related compounds with tyrosine and histidine. The bisazo compound of tyrosine and the bisazoamino compound of lysine were also characterized. In the second paper (2) we showed that the spectroscopic method can be app...
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ژورنال
عنوان ژورنال: ScienceAsia
سال: 2019
ISSN: 1513-1874
DOI: 10.2306/scienceasia1513-1874.2019.45.028